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Buehl, Christopher J; Goff, Noah J; Mikhova, Mariia; Hardwick, Steven W; Blundell, Thomas L; Modesti, Mauro; Schmidt, Jens C; Chaplin, Amanda; Meek, Katheryn.

Res Sq; 2023 Dec 13.

Artículo en Inglés | MEDLINE | ID: mdl-38168382

16.

BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors.

Misek, Sean A; Foda, Bardees M; Dexheimer, Thomas S; Akram, Maisah; Conrad, Susan E; Schmidt, Jens C; Neubig, Richard R; Gallo, Kathleen A.

Front Oncol; 12: 766794, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35444937

17.

A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics.

Sapoznik, Etai; Chang, Bo-Jui; Huh, Jaewon; Ju, Robert J; Azarova, Evgenia V; Pohlkamp, Theresa; Welf, Erik S; Broadbent, David; Carisey, Alexandre F; Stehbens, Samantha J; Lee, Kyung-Min; Marín, Arnaldo; Hanker, Ariella B; Schmidt, Jens C; Arteaga, Carlos L; Yang, Bin; Kobayashi, Yoshihiko; Tata, Purushothama Rao; Kruithoff, Rory; Doubrovinski, Konstantin; Shepherd, Douglas P; Millett-Sikking, Alfred; York, Andrew G; Dean, Kevin M; Fiolka, Reto P.

Elife; 92020 11 12.

Artículo en Inglés | MEDLINE | ID: mdl-33179596

18.

Dynamics of human telomerase recruitment depend on template-telomere base pairing.

Schmidt, Jens C; Zaug, Arthur J; Kufer, Regina; Cech, Thomas R.

Mol Biol Cell; 29(7): 869-880, 2018 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-29386295

19.

Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.

Shukla, Siddharth; Schmidt, Jens C; Goldfarb, Katherine C; Cech, Thomas R; Parker, Roy.

Nat Struct Mol Biol; 23(4): 286-92, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-26950371

20.

A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression.

Xi, Linghe; Schmidt, Jens C; Zaug, Arthur J; Ascarrunz, Dante R; Cech, Thomas R.

Genome Biol; 16: 231, 2015 Nov 10.

Artículo en Inglés | MEDLINE | ID: mdl-26553065

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Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres.

Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits.

Advances in understanding telomerase assembly.

Human telomerase: biogenesis, trafficking, recruitment, and activation.

Observation of processive telomerase catalysis using high-resolution optical tweezers.

Very fast nucleotides on demand.

Tracking the transition from an ATG9A vesicle to an autophagosome.

Live cell single-molecule imaging to study DNA repair in human cells.

Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation.

AMPK Regulates Phagophore-to-Autophagosome Maturation.

RHINO restricts MMEJ activity to mitosis.

Systematic analysis of the molecular and biophysical properties of key DNA damage response factors.

RHINO directs MMEJ to repair DNA breaks in mitosis.

TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly.

Unravelling the complexities of DNA-PK activation by structure-based mutagenesis.

BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors.

A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics.

Dynamics of human telomerase recruitment depend on template-telomere base pairing.

Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.

A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression.